IgG4 related fibrosis is rare condition with little data available on its diagnosis and treatment. No specific diagnostic markers were developed for this indication to date. A group of researchers from Nagasaki took an aim at identifying potential biomarker specific for IGG4 related disease (IgG4 RD).
Even with currently available treatment modalities, ESRD is a common complication of Granulomatosis with polyangiitis (GPA) occurring in approximately 25% of patients. Transplantation frequently used for ESRD but has not been applied widely in GPA.
Current analysis is aimed at evaluation of benefits of transplantation in extending surgical or prisons with GPA comparing to remaining on waiting list.